‌Photodynamic Therapy (PDT) Treatment Guide for Clinics and salons

1. Introduction to PDT‌

Photodynamic Therapy (PDT) is a minimally invasive treatment that uses light-sensitive compounds (photosensitizers) and light sources to destroy abnormal cells. It is widely used for skin conditions (e.g., acne, actinic keratosis), certain cancers, and infections. This guide outlines the step-by-step procedure, safety measures, and post-treatment care for PDT using a PDT machine.

‌2. Pre-Treatment Preparation‌

‌2.1 Patient Assessment‌

• ‌Medical History‌: Check for photosensitivity, allergies, or medications that may increase light sensitivity (e.g., tetracyclines).
• ‌Skin Test‌: Apply a small amount of photosensitizer (e.g., methyl aminolevulinate, ALA) to confirm tolerance.
• ‌Consent‌: Explain potential side effects (redness, swelling, temporary hyperpigmentation).

‌2.2 Equipment Setup‌

• ‌PDT Machine‌: Ensure the device is calibrated for the target wavelength (typically 630–670 nm for skin applications).
• ‌Photosensitizer‌: Select the appropriate type (e.g., Levulan for actinic keratosis) and apply evenly to the treatment area.
• ‌Protective Gear‌: Provide opaque goggles for patients and staff to shield eyes from intense light.

‌3. Treatment Procedure‌

‌3.1 Photosensitizer Activation‌

1. ‌Application‌: Spread the photosensitizer on the target area and cover it with an occlusive dressing.
2. ‌Incubation Time‌: Allow 30–60 minutes (varies by condition) for absorption into abnormal cells.

‌3.2 Light Exposure‌

1. ‌Cleanse the Area‌: Remove excess photosensitizer before illumination.
2. ‌Light Delivery‌:
   • Adjust the PDT machine to the recommended intensity (e.g., 100–150 mW/cm² for skin).
   • Expose the area for 10–20 minutes, ensuring uniform coverage.
   • Monitor for discomfort (burning sensation) and pause if necessary.

‌4. Post-Treatment Care‌

• ‌Immediate Aftercare‌:
  • Apply a cold compress to reduce inflammation.
  • Prescribe analgesics (e.g., acetaminophen) for pain relief.
• ‌Long-Term Care‌:
  • Avoid direct sunlight for 48 hours; use SPF 50+ sunscreen.
  • Hydrate the skin with fragrance-free moisturizers.
  • Schedule follow-ups to assess healing (typically 1–2 weeks post-treatment).

‌5. Safety and Troubleshooting‌

• ‌Adverse Reactions‌:
  • Severe Burns: Terminate treatment and apply aloe vera gel.
  • Infection: Use antibiotic ointment if signs of pus or fever appear.
• ‌Machine Maintenance‌:
  • Regularly check LED/light source efficacy.
  • Replace cooling fans if overheating occurs.

‌6. Conclusion‌

PDT machines offer precise, tissue-sparing treatment for dermatological and oncological conditions. Adhering to this guide ensures optimal outcomes while minimizing risks. Continuous training and adherence to protocols are vital for safe and effective PDT administration.

This guide combines clinical protocols with practical tips for PDT machine users. Adjustments may be needed based on specific device models or patient conditions. Let me know if you’d like to emphasize certain sections (e.g., pediatric PDT or advanced cancer applications).